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| Reporter | guest | Assigned To | | |
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| Priority | normal | Severity | minor | Reproducibility | have not tried |
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| Status | new | Resolution | open | |
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| Platform | sBgzLCfnbg | OS | UXdsDUpSkXDUB | |
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| Summary | 0000669: The National Gallery [url=http://www.dapurponcol.com/buy-cialis-at-walgreens-v3kt]buy cialis online malaysia[/url] The research |
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| Description | The National Gallery [url=http://www.dapurponcol.com/buy-cialis-at-walgreens-v3kt]buy cialis online malaysia[/url] The research team began by injecting all candidate genes into the human fibroblasts. They then systematically removed each one to see which were necessary for reprogramming, and which were dispensable. In the end, the team found that injecting a cocktail of five genes -- the 3-gene GMT mix plus the genes ESRRG and MESP1 -- were sufficient to reprogram the fibroblasts into heart-like cells. They then found that with the addition of two more genes, called MYOCD and ZFPM2, the transformation was even more complete. To help things along, the team initiated a chemical reaction known as the TGF-ß signaling pathway during the early stages of reprogramming, which further improved reprogramming success rates.
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| Steps To Reproduce | The National Gallery [url=http://www.dapurponcol.com/buy-cialis-at-walgreens-v3kt]buy cialis online malaysia[/url] The research team began by injecting all candidate genes into the human fibroblasts. They then systematically removed each one to see which were necessary for reprogramming, and which were dispensable. In the end, the team found that injecting a cocktail of five genes -- the 3-gene GMT mix plus the genes ESRRG and MESP1 -- were sufficient to reprogram the fibroblasts into heart-like cells. They then found that with the addition of two more genes, called MYOCD and ZFPM2, the transformation was even more complete. To help things along, the team initiated a chemical reaction known as the TGF-ß signaling pathway during the early stages of reprogramming, which further improved reprogramming success rates.
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| Additional Information | The National Gallery [url=http://www.dapurponcol.com/buy-cialis-at-walgreens-v3kt]buy cialis online malaysia[/url] The research team began by injecting all candidate genes into the human fibroblasts. They then systematically removed each one to see which were necessary for reprogramming, and which were dispensable. In the end, the team found that injecting a cocktail of five genes -- the 3-gene GMT mix plus the genes ESRRG and MESP1 -- were sufficient to reprogram the fibroblasts into heart-like cells. They then found that with the addition of two more genes, called MYOCD and ZFPM2, the transformation was even more complete. To help things along, the team initiated a chemical reaction known as the TGF-ß signaling pathway during the early stages of reprogramming, which further improved reprogramming success rates.
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